“Although symptoms were transient and most patients appeared to respond to treatment (solely with NSAIDS), we demonstrated persistence of abnormal findings on CMR at follow up in most patients, albeit with improvement in extent of LGE (a measure of the heart’s capacity to pump efficiently).”
The end of the first paragraph of the discussion section reflects this: The authors found that, although there was some measure of resolution after three to eight months, most subjects still had some persistent abnormalities. The authors used Electrocardiograms and Cardiac Magnetic Resonance (CMR) to examine abnormalities in the heart such as myocardial scarring, fibrosis, strain, and reduced ventricular muscle extension, which can be associated with reduced capacity to pump blood and increased risk of heart attack. This group had a median age of fifteen years.
Sixteen patients who had both acute phase and follow-up CMR available for review comprised the final cohort. One patient was excluded as initial CMR was performed three weeks after presentation. Six patients were excluded as they did not have a follow up CMR, either because they followed up out of state or a study is still pending. Twelve patients were excluded as they never had CMR due to delayed presentation after initial symptoms resolved or admission to other centers. 7, 2022, of patients younger than eighteen who came to the hospital with chest pain and an elevated serum troponin level within one week of receiving a second dose of the Pfizer shot.Ī total of thirty-five patients with the diagnosis of myopericarditis associated with Pfizer COVID-19 mRNA vaccine were followed at this institution. Researchers at Seattle Children’s Hospital reviewed cases that occurred between Apand Jan. A peer-reviewed, follow-up study published Main the Journal of Pediatrics showed more than two-thirds of adolescents with COVID-19 shots related myopericarditis had persistent heart abnormalities months after their initial diagnosis.
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